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Evaluating Chronic Obstructive Pulmonary Disease

By Jonathan Glauser, MD, FACEP, and James O’Hora, MD | on June 14, 2024 | 0 Comment
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Those with severe dyspnea, significantly decreased level of consciousness, persistent or worsening hypoxemia and/or severe or worsening respiratory acidosis (e.g., pH less than 7.25) despite supplemental oxygen and NIV, respiratory failure requiring intubation, or hemodynamic instability requiring vasoactive medications should be admitted to an intensive care unit for further careful management.4

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ACEP Now: Vol 43 – No 06 – June 2024

Dr. GlauserDr. Glauser is professor of emergency medicine at Case Western Reserve University at MetroHealth Cleveland Clinic in Cleveland.

Dr. O’Hora is an emergency medicine physician in Cleveland Heights, Ohio.

References

  1. Abdo WF, Heunks LMA. Oxygen-induced hypercapnia in COPD: myths and facts. Crit Care. 2012;16(5):323.
  2. Adeloye D, Song P, Zhu Y, et al. Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis. Lancet Respir Med. 2022;10(5):447-458.
  3. Canut A, Martín-Herrero JE, Labora A, et al. What are the most appropriate antibiotics for the treatment of acute exacerbation of chronic obstructive pulmonary disease? A therapeutic outcomes model. J Antimicrob Chemother. 2007;60(3):605-612.
  4. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (2023 report). https://goldcopd.org/2023-gold-report-2/. Updated Feb. 17, 2023. Accessed May 19, 2024.
  5. Howton JC, Rose J, Duffy S, et al. Randomized, double-blind, placebo-controlled trial of intravenous ketamine in acute asthma. Ann Emerg Med. 1996;27(2):170-175.
  6. Leuppi JD, Schuetz P, Bingisser R, et al. Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial. JAMA. 2013;309(21):2223-2231.
  7. Miravitlles M, Moragas A, Hernández S, et al. Is it possible to identify exacerbations of mild to moderate COPD that do not require antibiotic treatment?Chest. 2013;144(5):1571-1577.
  8. O’Driscoll BR, Smith R. Oxygen use in critical illness. Respir Care. 2019;64(10):1293-1307.
  9. Parrilla FJ, Morán I, Roche-Campo F, et al. Ventilatory strategies in obstructive lung disease. Semin Respir Crit Care Med. 2014;35(4):431-440.
  10. Quon BS, Gan WQ, Sin DD. Contemporary management of acute exacerbations of COPD: a systematic review and meta-analysis. Chest. 2008;133(3):756-766.
  11. Tintinalli JE, Stapczynski JS, Ma OJ, et al, eds. Tintinalli’s Emergency Medicine: A Comprehensive Study Guide. Ninth edition. New York, N.Y.: McGraw-Hill Education; 2020.
  12. van Geffen WH, Douma WR, Slebos DJ, et al. Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD. Cochrane Database Syst Rev. 2016;2016(8):CD011826.
  13. Vollenweider DJ, Frei A, Steurer-Stey CA, et al. Antibiotics for exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2018;10(10):CD010257.
  14. Wedzicha JA, Miravitlles M, Hurst JR, et al. Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline. Eur Respir J. 2017;49(3):1600791.
  15. Weingart SD. Managing initial mechanical ventilation in the emergency department. Ann Emerg Med. 2016;68(5):614-617.
  16. Wilson R, Jones P, Schaberg T, et al. Antibiotic treatment and factors influencing short and long term outcomes of acute exacerbations of chronic bronchitis. Thorax. 2006;61(4):337-342.
  17. Naghavi M, Wang H, Lozano R, et al. Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385(9963):117-171.

Pages: 1 2 3 4 5 | Single Page

Topics: acute exacerbations of COPD (AECOPD)chronic obstructive pulmonary diseaseCOPDGOLD

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