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Direct Oral Anticoagulants

  • Anticoagulant Selection Is Cornerstone of Pulmonary Embolism Treatment

    The treatment of patients with pulmonary embolism (PE) has evolved substantially over the past few decades. Many...
  • Not All DOACs Have Same GI-Bleeding Risk

    Rivaroxaban is associated with higher rates of gastrointestinal bleeding compared with other direct oral anticoagulants (DOACs), regardless...
  • DOAC-prompted Bleeding Fatal in Some Patients, Despite Successful Reversal in Many

    Despite a high rate of effective hemostasis with reversal agents following major bleeding tied to direct oral...

Anticoagulant Selection Is Cornerstone of Pulmonary Embolism Treatment

March 11, 2025 - Lauren Westafer, DO, MPH, MS, FACEP - 1 Comment

The treatment of patients with pulmonary embolism (PE) has evolved substantially over the past few decades. Many…

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Not All DOACs Have Same GI-Bleeding Risk

November 23, 2021 - Reuters Staff - 0 Comment

Rivaroxaban is associated with higher rates of gastrointestinal bleeding compared with other direct oral anticoagulants (DOACs), regardless…

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DOAC-prompted Bleeding Fatal in Some Patients, Despite Successful Reversal in Many

June 18, 2021 - David Douglas (Reuters Health) - 0 Comment

Despite a high rate of effective hemostasis with reversal agents following major bleeding tied to direct oral…

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Outpatient Management of Pulmonary Embolism

June 15, 2021 - Lauren Westafer, DO, MPH - 1 Comment

Historically, patients diagnosed with pulmonary embolism (PE) initially have been managed as inpatients. This practice stemmed from…

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A Case Example: Reversing Anticoagulant Dabigatran with Idarucizumab

February 5, 2019 - W. Richard Bukata, MD - 0 Comment

The Case A 75-year-old man presents to your emergency department via paramedics. His transport time was about…

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New-Drug Details: Reversing Anticoagulant Dabigatran with Idarucizumab

February 5, 2019 - Mary Choy, PharmD, BCGP, FASHP - 1 Comment

Idarucizumab (Praxbind) is the first and only specific reversal agent for a novel oral anticoagulant (NOAC) approved…

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Should You Use Direct Oral Anticoagulants for Cancer-Associated VTE?

January 13, 2019 - Ken Milne, MD - 1 Comment

The Case A 73-year-old man currently undergoing chemotherapy for colon cancer presents to the emergency department with…

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New Developments in Direct Oral Anticoagulant Safety and Indications

September 14, 2015 - Ryan Patrick Radecki, MD, MS - 0 Comment

Much has changed in the realm of oral anticoagulation over the past few years. Beginning with the…

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