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What the Data Say about TXA as for Trauma

By Ryan Patrick Radecki, MD, MS | on December 20, 2019 | 0 Comment
CME CME Now Pearls From the Medical Literature
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References

  1. WOMAN trial collaborators. Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. Lancet. 2017;389(10084):2105-2116.
  2. McNeil DG. Inexpensive drug prevents deaths in new mothers, study finds. The New York Times. Apr 26, 2017. Accessed Nov. 21, 2019.
  3. CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. Lancet. 2019;394(10210):1713-1723.
  4. Davis N. Common drug could prevent thousands of head injury deaths. The Guardian. Oct. 14, 2019. Accessed Nov. 21, 2019.
  5. Shakur H, Roberts I, Bautista R, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet. 2010;376(9734):23-32.
  6. Sprigg N, Flaherty K, Appleton JP, et al. Tranexamic acid for hyperacute primary intracerebral haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial. Lancet. 2018;391(10135):2107-2115.

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Explore This Issue
ACEP Now: Vol 38 – No 12 – December 2019

Pages: 1 2 3 | Single Page

Topics: CMECME Nowhead injuryTranexamic AcidTrauma and Injury

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About the Author

Ryan Patrick Radecki, MD, MS

Ryan Patrick Radecki, MD, MS, is an emergency physician and informatician with Christchurch Hospital in Christchurch, New Zealand. He is the Annals of Emergency Medicine podcast co-host and Journal Club editor and can be found on Twitter @emlitofnote.

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