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Spinal Epidural Abscess—Avoiding Neurologic Catastrophe in the ED

By ACEP Now | on April 1, 2010 | 0 Comment
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Learning Objectives

After reading this article, the physician should be able to:

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  • Identify and describe risk factors for epidural abscess.
  • Identify ED findings that should prompt consideration of spinal epidural abscess as a diagnosis.
  • Identify radiographic and laboratory abnormalities associated with epidural abscess.
  • Describe treatment approaches based on current evidence.

Case Presentation

History: A 39-year-old male with a history of hepatitis C and polysubstance abuse presents with acute onset lower extremity paralysis and paresthesia, bilateral upper extremity weakness, and diffuse neck pain. He admits to falling from a standing height about 1 week prior, but states he was seen at another facility and discharged in good condition except for persistent neck pain. Review of systems is otherwise negative, and the patient has no previous history of similar episodes.

Physical Exam: Afebrile, well appearing, with normal vital signs. Physical examination is normal except for the following abnormal neurological findings: exquisite tenderness to palpation at C6 spinous process, bilateral upper extremity weakness (2/5) with normal deep tendon reflexes, bilateral lower extremity paralysis (0/5) with absent deep tendon reflexes, weakness of grip strength bilaterally, normal tone, and Babinski negative bilaterally. Ambulation and gait cannot be tested. Finger-to-nose testing is normal. Proprioception is intact bilaterally. There is absent perineal sensation. Weak contracture of the anal sphincter noted, but no bulbocavernosus reflex could be elicited.

Management: Laboratory studies and chest x-ray are normal. CT scan of head and cervical spine demonstrate no intracerebral abnormality but do show degenerative changes of the spine, most prominent at the C4-C7 levels; the canal diameter, however, is normal.

Neurosurgical consultation is requested for persistent lower extremity paralysis. An MRI is ordered, and high-dose methylprednisolone intravenous infusion started. The MRI reveals pre-vertebral soft tissue swelling from C2-C7 and increased T2-signal extending from C5-C6 within the epidural space and extending posteriorly 5 mm. There is associated cervical cord compression suggesting early abscess formation. The patient is taken for emergent neurosurgical decompression and drainage. Cultures were positive for Staphylococcus aureus. Patient is discharged home 15 days later able to ambulate but with residual lower extremity weakness.

Key Points

  • Lumbar puncture is contraindicated in spinal epidural abscess.
  • Epidural abscess should be considered in any patient with localized back tenderness and at least one risk factor.
  • Immediate neurosurgical evaluation should not be delayed, even in patients who are neurologically intact.
  • MRI with gadolinium is the study of choice for diagnosis of SEA.

Introduction

Back pain is second only to respiratory complaints as a reason for primary care visits, with 90%-95% having a non-life–threatening condition1,2 and 85% recovering in 4-6 weeks without intervention.1-3 The other 5%-10% of cases, however, may harbor a more serious pathology and warrant further diagnostic evaluation in the emergency department.

Pages: 1 2 3 4 5 6 7 | Single Page

Topics: Clinical GuidelineCMECritical CareDiagnosisEducationEmergency MedicineEmergency PhysicianImaging and UltrasoundNeurologyPainPatient SafetyProcedures and SkillsQuality

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