“INNDs may still have a place in overdose reversal, but their potential limitations must be considered,” he said. “These results showed a lower blood naloxone level after INND use, but the clinical significance of this difference is unknown.”
“It is worth adding that there are many unpredictable factors that can cause these antidotes to fail, and emergency services should also be contacted for a suspected overdose even if naloxone is successfully used,” Dr. Eggleston said.
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