Logo

Log In Sign Up |  An official publication of: American College of Emergency Physicians
Navigation
  • Home
  • Multimedia
    • Podcasts
    • Videos
  • Clinical
    • Airway Managment
    • Case Reports
    • Critical Care
    • Guidelines
    • Imaging & Ultrasound
    • Pain & Palliative Care
    • Pediatrics
    • Resuscitation
    • Trauma & Injury
  • Resource Centers
    • mTBI Resource Center
  • Career
    • Practice Management
      • Benchmarking
      • Reimbursement & Coding
      • Care Team
      • Legal
      • Operations
      • Quality & Safety
    • Awards
    • Certification
    • Compensation
    • Early Career
    • Education
    • Leadership
    • Profiles
    • Retirement
    • Work-Life Balance
  • Columns
    • ACEP4U
    • Airway
    • Benchmarking
    • Brief19
    • By the Numbers
    • Coding Wizard
    • EM Cases
    • End of the Rainbow
    • Equity Equation
    • FACEPs in the Crowd
    • Forensic Facts
    • From the College
    • Images in EM
    • Kids Korner
    • Medicolegal Mind
    • Opinion
      • Break Room
      • New Spin
      • Pro-Con
    • Pearls From EM Literature
    • Policy Rx
    • Practice Changers
    • Problem Solvers
    • Residency Spotlight
    • Resident Voice
    • Skeptics’ Guide to Emergency Medicine
    • Sound Advice
    • Special OPs
    • Toxicology Q&A
    • WorldTravelERs
  • Resources
    • ACEP.org
    • ACEP Knowledge Quiz
    • Issue Archives
    • CME Now
    • Annual Scientific Assembly
      • ACEP14
      • ACEP15
      • ACEP16
      • ACEP17
      • ACEP18
      • ACEP19
    • Annals of Emergency Medicine
    • JACEP Open
    • Emergency Medicine Foundation
  • About
    • Our Mission
    • Medical Editor in Chief
    • Editorial Advisory Board
    • Awards
    • Authors
    • Article Submission
    • Contact Us
    • Advertise
    • Subscribe
    • Privacy Policy
    • Copyright Information

Drugs for Immediate Relief of Cannabinoid Hyperemesis Syndrome

By Lauren Westafer, DO | on February 24, 2021 | 3 Comments
Practice Changers
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
Print-Friendly Version
shutterstock.com

Dr. WestaferDr. Westafer (@LWestafer) is assistant professor of emergency medicine and emergency medicine research fellowship director at the University of Massachusetts Medical School–Baystate, and co-host of FOAMcast.

You Might Also Like
  • Intoxication from Synthetic-Cannabinoid-Receptor Agonists Often Missed
  • Fentanyl Versus Ketamine for Intranasal Pain Relief
  • Acute Chest Syndrome in Pediatric Sickle-Cell Disease: Antibiotic Guidelines Matter
Explore This Issue
ACEP Now: Vol 40 – No 02 – February 2021

References

  1. Allen JH, de Moore GM, Heddle R, et al. Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse. Gut. 2004;53(11):1566-1570.
  2. Simonetto DA, Oxentenko AS, Herman ML, et al. Cannabinoid hyperemesis: a case series of 98 patients. Mayo Clin Proc. 2012;87(2):114-119.
  3. Chang YH, Windish DM. Cannabinoid hyperemesis relieved by compulsive bathing. Mayo Clin Proc. 2009;84(1):76-78.
  4. Lee C, Greene SL, Wong A. The utility of droperidol in the treatment of cannabinoid hyperemesis syndrome. Clin Toxicol (Phila). 2019;57(9):773-777.
  5. Ruberto AJ, Sivilotti MLA, Forrester S, et al. Intravenous haloperidol versus ondansetron for cannabis hyperemesis syndrome (HaVOC): a randomized, controlled trial. Ann Emerg Med. 2020;S0196-0644(20)30666-1.
  6. Dezieck L, Hafez Z, Conicella A, et al. Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series. Clin Toxicol (Phila). 2017;55(8):908-913.
  7. Graham J, Barberio M, Wang GS. Capsaicin cream for treatment of cannabinoid hyperemesis syndrome in adolescents: a case series. Pediatrics. 2017;140:e20163795.
  8. Moon AM, Buckley SA, Mark NM. Successful treatment of cannabinoid hyperemesis syndrome with topical capsaicin. ACG Case Rep J. 2018;5:e3.
  9. Wagner S, Hoppe J, Zuckerman M, et al. Efficacy and safety of topical capsaicin for cannabinoid hyperemesis syndrome in the emergency department. Clin Toxicol (Phila). 2020;58(6):471-475.
  10. Dean DJ, Sabagha N, Rose K, et al. A pilot trial of topical capsaicin cream for treatment of cannabinoid hyperemesis syndrome. Acad Emerg Med. 2020;27(11):1166-1172.

Pages: 1 2 3 | Single Page

Topics: butyrophenonesCannabinoidcannabinoid hyperemesis syndromecapsaicindroperidolhaloperidolMarijuana

Related

  • Case Report: Uvular Edema in a Marijuana Smoker

    November 5, 2024 - 0 Comment
  • Toxicology Answer: The Capsaicin Found in Hot Peppers and Chilis

    April 2, 2024 - 0 Comment
  • Toxicology Question: What Fiery Ingredient Brings Tears to Your Eyes and Irritation Upon Exposure?

    April 1, 2024 - 0 Comment

Current Issue

ACEP Now: November 2025

Download PDF

Read More

3 Responses to “Drugs for Immediate Relief of Cannabinoid Hyperemesis Syndrome”

  1. February 28, 2021

    Edward L Fieg Reply

    In my experience, one of the hallmarks of Cannabis Hyperemesis Syndrome, is that the patient, minimiing their cannabis use, absolutely, positively, will not even consider to entertain any discussion of the possibility that the cannabis is the culprit.

  2. February 28, 2021

    Frank Fower,MD,FACEP Reply

    I have been using the same: Haldol or Inapsin to treat such cases even before 2004…
    I give 50 mg Benadryl IV with it , It’s Synergistic effect and prevents EPS and prevents prolongation of QT interval

    • November 28, 2024

      Isaac Okoni Reply

      Can soursop beverage help in alleviating CHS?

Leave a Reply Cancel Reply

Your email address will not be published. Required fields are marked *


*
*


Wiley
  • Home
  • About Us
  • Contact Us
  • Privacy
  • Terms of Use
  • Advertise
  • Cookie Preferences
Copyright © 2025 by John Wiley & Sons, Inc. All rights reserved, including rights for text and data mining and training of artificial technologies or similar technologies. ISSN 2333-2603