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Does Administering Steroids for Cardiac Arrest Lead to Better Neurological Outcomes?

By Ken Milne, MD | on July 21, 2021 | 0 Comment
Skeptics' Guide to EM
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Should steroids be part of your cardiac arrest protocol?

References

  1. Nielsen N, Wetterslev J, Cronberg T, et al. Targeted temperature management at 33°C versus 36°C after cardiac arrest. N Engl J Med. 2013;369(23):2197-2206.
  2. Kawano T, Grunau B, Scheuermeyer FX, et al. Intraosseous vascular access is associated with lower survival and neurologic recovery among patients with out-of-hospital cardiac arrest. Ann Emerg Med. 2018;71(5):588-596.
  3. Benger JR, Kirby K, Black S, et al. Effect of a strategy of a supraglottic airway device vs tracheal intubation during out-of-hospital cardiac arrest on functional outcome: the AIRWAYS-2 randomized clinical trial. JAMA. 2018;320(8):779-791.
  4. Wang HE, Schmicker RH, Daya MR, et al. Effect of a strategy of initial laryngeal tube insertion vs endotracheal intubation on 72-hour survival in adults with out-of-hospital cardiac arrest: a randomized clinical trial. JAMA. 2018;320(8):769-778.
  5. Derkenne C, Jost D, Roquet F, et al. Mobile smartphone technology is associated with out-of-hospital cardiac arrest survival improvement: the first year “Greater Paris Fire Brigade” experience. Acad Emerg Med. 2020;27(10):951-962.
  6. Gates S, Quinn T, Deakin CD, et al. Mechanical chest compression for out of hospital cardiac arrest: systematic review and meta-analysis. Resuscitation. 2015;94:91-97.
  7. Mentzelopoulos SD, Malachias S, Chamos C, et al. Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized clinical trial. JAMA. 2013;310(3):270-279.
  8. Paris PM, Stewart RD, Deggler F. Prehospital use of dexamethasone in pulseless idioventricular rhythm. Ann Emerg Med. 1984;13(11):1008-1010.
  9. Liu B, Zhang Q, Li C. Steroid use after cardiac arrest is associated with favourable outcomes: a systematic review and meta-analysis. J Int Med Res. 2020;48(5):300060520921670.
  10. Baker M. 1,500 scientists lift the lid on reproducibility. Nature. 2016;533(7604):452-454.

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Explore This Issue
ACEP Now: Vol 40 – No 07 – July 2021

Pages: 1 2 3 | Single Page

Topics: CardiacCardiac ArrestCorticosteroidsResuscitationSteroids

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About the Author

Ken Milne, MD

Ken Milne, MD, is chief of emergency medicine and chief of staff at South Huron Hospital, Ontario, Canada. He is on the Best Evidence in Emergency Medicine faculty and is creator of the knowledge translation project the Skeptics Guide to Emergency Medicine.

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