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Brain Trauma Guidelines for Emergency Medicine

By Andy Jagoda, MD; Ben Bobrow, MD; Al Lulla, MD; Jamshid Ghajar, MD; Greg Hawryluk, MD | on October 3, 2023 | 1 Comment
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  • airway re-positioning,
  • positive pressure ventilation as with bag-valve-mask ventilation in conjunction with appropriate airway adjuncts (e.g., oropharyngeal airway), and/or
  • supraglottic airway or endotracheal intubation by a trained health care professional.
  • An airway should be established, by the most appropriate means available, in patients who have signs of severe TBI, GCS < 9, or 9 and decompensating, the inability to maintain an adequate airway, or if hypoxemia is not corrected by supplemental oxygen.
  • Emergency Medical Service (EMS) systems implementing endotracheal intubation protocols including the use of rapid sequence intubation (RSI) protocols should confirm endotracheal tube placement in the trachea by the presence of bilateral breath sounds on auscultation, ETCO2 detection and/or capnography. Intubated patients in the prehospital setting require continuously monitored oxygenation, ETCO2, and frequent blood pressure monitoring.
  • Patients requiring respiratory support with positive pressure ventilation should be maintained with normal breathing rates (approximately 10 breaths per minute with ETCO2 35-45 mmHg), and hyperventilation (ETCO2 < 35 mmHg) should be avoided. Ventilatory adjuncts such as pressure-controlled bags, ventilation-rate timers, ETCO2 monitoring, and ventilators should be used to support appropriate ventilation and minimize the risk of secondary insults by avoiding hypo- and hyperventilation.
  • Fluid Resuscitation

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    Explore This Issue
    ACEP Now: Vol 42 – No 10 – October 2023
    • Intravenous fluids should be administered in the prehospital setting to treat hypotension and/or limit hypotension to the shortest duration possible.
    • Hypotensive patients should be treated with blood products and/or isotonic fluids in the prehospital setting.
    • Hypertonic fluid resuscitation may be administered to patients with a Glasgow Coma Scale Score (GCS) < 8 in whom increased ICP is suspected in the prehospital setting.

    Hyperventilation and Hyperosmolar Therapy for Suspected Increased Intracranial Pressure (ICP)

    • Hyperventilation should be avoided in the prehospital care of children and adults with TBI in the absence of signs of active cerebral herniation.
    • Ventilation strategies should target eucapnia and avoid hypocapnia (i.e., ETCO2 of 35- 40) and be monitored using capnography.
    • When used to address signs of active and imminent herniation, hyperventilation should target an ETCO2 of 30-35 using capnography.
    • Hyperosmolar therapy should not be administered for the prophylactic treatment of suspected elevated ICP, with or without signs of cerebral herniation, in the prehospital setting at this time.
    • Prehospital administration of TXA therapy is not generally and widely indicated for the prophylactic treatment of suspected ICH or elevated ICP at this time.[/sidebar]

    References

    1. Lulla A, et al. Prehospital Guidelines for the management of traumatic brain injury – 3rd edition. Prehosp Emerg Care. 2023; https://doi.org/10.1080/10903127.2023.2187905.
    2. Centers for Disease Control and Prevention. National Center for Health Statistics: Mortality Data on CDC WONDER. Accessed 2022, https://wonder.cdc.gov/mcd.html.
    3. Bell JM, Breiding MJ, DePadilla L. CDC’s efforts to improve traumatic brain injury surveillance. J Safety Res. 2017;62:253 -256.
    4. Spaite DW, Bobrow BJ, Keim SM, et al. Association of Statewide Implementation of the Prehospital Traumatic Brain Injury Treatment Guidelines With Patient Survival Following Traumatic Brain Injury: The Excellence in Prehospital Injury Care (EPIC) Study. JAMA Surg. 2019;154(7):e191152.

    DECISION-MAKING WITHIN THE EMS SYSTEM

    Pages: 1 2 3 4 5 | Single Page

    Topics: ClinicalGuidelinesTrauma & InjuryTraumatic Brain Injury

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    One Response to “Brain Trauma Guidelines for Emergency Medicine”

    1. April 9, 2025

      Cristopher Astudillo Reply

      Me pareció interesante. Una información bastante valiosa para el tratamiento de TCE.

      Con cuerdo mucho con uno de los partidos que dice “El tratamiento inmediato del TCE, desde la APH da una buena probabilidad de vida a los pacientes” es algo fundamental para prevenir lesiones secundarias y mejorar el tiempo de recuperación del paciente.

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