Logo

Log In Sign Up |  An official publication of: American College of Emergency Physicians
Navigation
  • Home
  • Multimedia
    • Podcasts
    • Videos
  • Clinical
    • Airway Managment
    • Case Reports
    • Critical Care
    • Guidelines
    • Imaging & Ultrasound
    • Pain & Palliative Care
    • Pediatrics
    • Resuscitation
    • Trauma & Injury
  • Resource Centers
    • mTBI Resource Center
  • Career
    • Practice Management
      • Benchmarking
      • Reimbursement & Coding
      • Care Team
      • Legal
      • Operations
      • Quality & Safety
    • Awards
    • Certification
    • Compensation
    • Early Career
    • Education
    • Leadership
    • Profiles
    • Retirement
    • Work-Life Balance
  • Columns
    • ACEP4U
    • Airway
    • Benchmarking
    • Brief19
    • By the Numbers
    • Coding Wizard
    • EM Cases
    • End of the Rainbow
    • Equity Equation
    • FACEPs in the Crowd
    • Forensic Facts
    • From the College
    • Images in EM
    • Kids Korner
    • Medicolegal Mind
    • Opinion
      • Break Room
      • New Spin
      • Pro-Con
    • Pearls From EM Literature
    • Policy Rx
    • Practice Changers
    • Problem Solvers
    • Residency Spotlight
    • Resident Voice
    • Skeptics’ Guide to Emergency Medicine
    • Sound Advice
    • Special OPs
    • Toxicology Q&A
    • WorldTravelERs
  • Resources
    • ACEP.org
    • ACEP Knowledge Quiz
    • Issue Archives
    • CME Now
    • Annual Scientific Assembly
      • ACEP14
      • ACEP15
      • ACEP16
      • ACEP17
      • ACEP18
      • ACEP19
    • Annals of Emergency Medicine
    • JACEP Open
    • Emergency Medicine Foundation
  • About
    • Our Mission
    • Medical Editor in Chief
    • Editorial Advisory Board
    • Awards
    • Authors
    • Article Submission
    • Contact Us
    • Advertise
    • Subscribe
    • Privacy Policy
    • Copyright Information

Acetaminophen Overdose Diagnosis and Treatment

By Kristen C. Peña, DO; and John S. Kashani, DO | on July 18, 2018 | 0 Comment
Features
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
Print-Friendly Version

The Case

ILLUSTRATION: Chris Whissen & shutterstock.com

You Might Also Like
  • Critical Decisions: Acetaminophen Toxicity
  • Acetaminophen Overdose—Was It Extended- or Immediate-Release Pills?
  • Naloxone Nasal Spray Approved by FDA for Opioid Overdose Treatment
Explore This Issue
ACEP Now: Vol 37 – No 07 – July 2018

ILLUSTRATION: Chris Whissen & shutterstock.com

The patient is a 17-year-old non-English-speaking Bengali female with no past medical history who presented to the pediatric emergency department at 12:30 a.m. with complaints of abdominal pain, vomiting, and headache that began earlier that evening. She is accompanied by her mother, younger sister, and a male neighbor who was asked to come to help translate. She describes the abdominal pain as diffuse in nature without localization, with more than 15 episodes of non-bloody, non-bilious emesis. There is no food exposure to account for her symptoms as she has not had anything to eat that day. Her last menstrual period was about 20 days prior to ED visit and was normal. She denies recent travel, fever, chills, urinary symptoms, diarrhea, sick contacts, or taking medications for her symptoms.

On exam, she appears pale and uncomfortable, with dry mucous membranes. However, she is awake, alert, and oriented, with a Glasgow Coma Scale score of 15. The abdominal exam reveals mild diffuse abdominal tenderness without radiation, rigidity, or guarding. IV access is obtained, and blood work is sent at 1 a.m. Her complete blood count, complete metabolic panel, lipase, urinalysis, and urine human chorionic gonadotropin are all within normal limits. She is treated with a 1 L normal saline bolus, Zofran 4 mg IV, Pepcid 20 mg IV, and ketorolac 30 mg IV, and her symptoms improve.

In the setting of normal blood work and no clear reason for the vomiting, a bedside ultrasound is performed to evaluate the right upper quadrant. The bedside ultrasound is negative for any acute biliary pathology. The patient at this point has changed into a hospital gown and is noted to have self-mutilation marks on her left forearm in the shape of an “M.” When asked about these marks on her arm, she states that she cut herself while cooking. It becomes obvious that there is more to the story. The family and neighbor are asked to step out of the room, and CyraCom translation service is brought to the bedside. The patient is not very cooperative with questioning, but when asked if she took any medications, she admits to taking 27 650 mg Tylenol tablets at 2:30 p.m., about 10 hours prior to arrival. She states she took the pills because she was feeling sad because her boyfriend, whose name begins with “M,” broke up with her.

Pages: 1 2 3 4 5 | Single Page

Topics: acetaminophenCase ReportsCritical CareHepatotoxicityOverdosesuicide

Related

  • Why the Nonrebreather Should be Abandoned

    December 3, 2025 - 0 Comment
  • Case Report: Massive Amitriptyline and Bupropion Ingestion

    October 29, 2025 - 0 Comment
  • Non-Invasive Positive Pressure Ventilation in the Emergency Department

    October 1, 2025 - 0 Comment

Current Issue

ACEP Now: November 2025

Download PDF

Read More

No Responses to “Acetaminophen Overdose Diagnosis and Treatment”

Leave a Reply Cancel Reply

Your email address will not be published. Required fields are marked *


*
*


Wiley
  • Home
  • About Us
  • Contact Us
  • Privacy
  • Terms of Use
  • Advertise
  • Cookie Preferences
Copyright © 2025 by John Wiley & Sons, Inc. All rights reserved, including rights for text and data mining and training of artificial technologies or similar technologies. ISSN 2333-2603