Delirium isn’t a harmless observation — it’s a red flag of serious underlying pathology. And although encephalopathy may underlie it, naming the process isn’t enough. Treat delirium as a syndrome that demands the question: What prompted this and what can we do about it? Use 4AT. Use structured frameworks. Document thoroughly. Protect patients and your practice.
Explore This Issue
ACEP Now: January 2026Let’s stop calling it “confusion.” Let’s start recognizing it as what it might be — delirium — and manage it accordingly. Our patients deserve nothing less.
Dr. Sonja Foo is a board-certified emergency medicine critical care physician completing her Neurocritical Care Fellowship at the Massachusetts General Hospital, Brigham and Women’s Hospital, and Harvard Medical School Training Program.
References
- Slooter AJC, Otte WM, Devlin JW, et al. Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies. Intensive Care Med. 2020;46(5):1020-1022
- Chen F, Liu L, Wang Y, et al. Delirium prevalence in geriatric emergency department patients: a systematic review and meta-analysis. Am J Emerg Med. 2022;59:121-128.
- Kennedy M, Enander RA, Tadiri SP, et al. Delirium risk prediction, healthcare use and mortality of elderly adults in the emergency department. J Am Geriatr Soc. 2014;62(3):462-9.
- Lee JS, Tong T, Chignell M, et al. Prevalence, management and outcomes of unrecognized delirium in a national sample of 1,493 older emergency department patients: how many were sent home and what happened to them? Age Ageing. 2022;51(2):afab214.
- Howick AS, Thao P, Carpenter KP, et al. Outcomes of older adults with delirium discharged from the emergency department. Ann Emerg Med. 2025:S0196-0644(25)00064-2.
- Goldberg TE, Chen C, Wang Y, et al. Association of delirium with long-term cognitive decline: a meta-analysis. JAMA Neurol. 2020;77(11):1373-1381. Erratum in: JAMA Neurol. 2020;77(11):1452.
- Shenkin SD, Fox C, Godfrey M, et al. Protocol for validation of the 4AT, a rapid screening tool for delirium: a multicentre prospective diagnostic test accuracy study. BMJ Open. 2018;8(2):e015572.
- Tieges Z, Maclullich AMJ, Anand A, et al. Diagnostic accuracy of the 4AT for delirium detection in older adults: systematic review and meta-analysis. Age Ageing. 2021;50(3):733-743.
- Jeong E, Park J, Lee J. Diagnostic test accuracy of the 4AT for delirium detection: a systematic review and meta-analysis. Int J Environ Res Public Health. 2020;17(20):7515.
- Shenkin SD, Fox C, Godfrey M, et al. Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method. BMC Med. 2019;17(1):138.
- Thomas J, Moore G. Medical-legal Issues in the agitated patient: cases and caveats. West J Emerg Med. 2013;14(5):559-65.
- Reeves RR, Pinkofsky HB, Stevens L. Medicolegal errors in the ED related to the involuntary confinement of psychiatric patients. Am J Emerg Med. 1998;16(7):631-3.
- Barstow C, Shahan B, Roberts M. Evaluating medical decision-making capacity in practice. Am Fam Physician. 2018;98(1):40-46.
- Griglak MJ, Bucci RL. Medicolegal management of the organically impaired patient in the emergency department. Ann Emerg Med. 1985;14(7):685-9.
- Ghaith S, Moore GP, Colbenson KM, Lindor RA. charting practices to protect against malpractice: case reviews and learning points. West J Emerg Med. 2022;23(3):412-417.
Pages: 1 2 3 4 | Single Page




No Responses to “A Practical Guide to Diagnosing Delirium and Acute Cognitive Change in the ED”