Last month, I highlighted some of the most impactful, talked-about, or interesting articles published across the spectrum of medical journals from the past year. Here are a few more key studies from 2017. As always, it is impossible to cover every important article or to cover them in the detail they deserve. Let this serve as a jumping-off point into the maelstrom, but I always encourage you to visit the primary source before making changes to your practice.
Prevalence of Pulmonary Embolism Among Patients Hospitalized for Syncope1
This controversial trial, PESIT, approached the issue of the prevalence of pulmonary embolism (PE) in syncope by mandating a D-dimer-based protocol for all patients admitted to the hospital with a diagnosis of syncope. Using their protocol, they found that nearly one in six patients admitted were diagnosed with PE. These data are not generalizable, as it does not appear an adequate emergency department workup for PE was performed initially, and it does not account for the vast cohort of patients with likely benign causes who were discharged rather than admitted. ED discharges were excluded.