A 48-year-old man presents to your ED complaining of a two-day history of a warm, painful, reddened area on his right shin. It started with a minor abrasion earlier in the week. He has no significant past medical history and no known drug allergies. There is no evidence of an abscess on examination, and his labs and vital signs are normal. He is diagnosed with uncomplicated cellulitis, and you plan to send him home with a five-day course of cephalexin but are thinking about giving him a “one for the road” single dose of IV cefazolin before he leaves.
What is the risk of emergency department patients developing antibiotic-associated diarrhea (AAD) with an IV dose of antibiotics prior to discharge?