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Acute Mesenteric Ischemia

By ACEP Now | on March 1, 2011 | 0 Comment
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Early consultation with interventional radiology and surgery is necessary for definitive management.

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ACEP News: Vol 30 – No 03 – March 2011

Endovascular interventions in hemodynamically stable patients include angioplasty, arterial stenting, aspiration embolectomy, and directed SMA thrombolysis.

Vasodilators are employed to reduce vasospasm. Specific agents include papaverine (a phosphodiesterase inhibitor) and glucagon. Papaverine’s standard dose is 30-60 mg/h via direct angiography catheter. Patients with peritoneal signs or concern for perforated bowel should prompt immediate surgical consultation. However, attempts at revascularization should precede surgical intervention when the clinical situation allows.8

Laparotomy is required for all patients who have evidence of any threatened bowel.15

Other surgical approaches include open embolectomy, thromboendarterectomy, and mesenteric artery bypass.

Acute mesenteric ischemia is a difficult clinical problem in part because of varying underlying etiologies and difficulty establishing the diagnosis.

A high index of suspicion is required, given the notable lack of simple, noninvasive testing available to confirm or exclude the diagnosis.

Early recognition and initiation of management are especially important given the high morbidity and mortality related to delay in diagnosis.

Suspect AMI in the elderly patient with a history of cardiac disease who presents with abdominal pain.

References

  1. O’Keefe KP and Sanson TG. Mesenteric ischemia. In: Adams JG, et al. Emergency Medicine, 2008, p. 331.
  2. Acosta S. Epidemiology of mesenteric vascular disease. Semin Vasc Surg 2010 Mar;23(1):4-8.
  3. Ruotolo RA, et al. Mesenteric ischemia in the elderly. Clin Geriatr Med 1999;15(3):527-57.
  4. Oldenburg WA, et al. Acute mesenteric ischemia. Arch Intern Med 2004;164:1054-62.
  5. Brandt LJ and Boley SJ. AGA technical review on intestinal ischemia. Gastroenterology 2000;118:954-68.
  6. Yasuhara H. Acute mesenteric ischemia: The challenge of gastroenterology. Surg Today 2005;35:185-95.
  7. Hendrickson M and Naparst TR. Abdominal surgical emergencies in the elderly. Emerg Med Clinic North Am 2003;21:937-69.
  8. Evennett NJ, et al. Systematic review and pooled estimates for the diagnostic accuracy of serological markers for intestinal ischemia. World J Surg 2009;33:1374-83.
  9. Berland T and Oldenburg WA. Acute mesenteric ischemia. Curr Gastroenterol Rep 2008;10(3):341-6.
  10. Taourel PG, et al. Acute mesenteric ischemia: Diagnosis with contrast-enhanced CT. Radiology 1996;199(3):632-6.
  11. Kirkpatrick ID, et al. Biphasic CT with mesenteric CT angiography in the evaluation of acute mesenteric ischemia. Radiology 2003;229(1):91-8.
  12. Ofer A, et al. Multidetector CT angiography in the evaluation of acute mesenteric ischemia. Eur Radiol 2009 Jan;19(1):24-30.
  13. Menke J. Diagnostic accuracy of multidetector CT in acute mesenteric ischemia: systematic review and meta-analysis. Radiology 2010;256(1):93-101.
  14. Chow LC, et al. A comprehensive approach to MR imaging of mesenteric ischemia. Abdom Imaging 2002;27:507-16.
  15. Wyers MC. Acute mesenteric ischemia: Diagnostic approach and surgical treatment. Semin Vasc Surg 2010;23(1):9-20.

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Topics: Abdominal and GastrointestinalAdmissionCardiovascularClinical ExamCMECritical CareDiagnosisEducationEmergency MedicineEmergency PhysicianImaging and UltrasoundProcedures and SkillsTrauma and Injury

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