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ACEP Clinical Policy on Intravenous Tissue Plasmogen for Stroke Continues to Evolve

By Ryan Patrick Radecki, MD, MS | on March 16, 2015 | 2 Comments
Pearls From the Medical Literature
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Explore This Issue
ACEP Now: Vol 34 – No 03 – March 2015

Dr. RadeckiDr. Radecki is assistant professor of emergency medicine at The University of Texas Medical School at Houston. He blogs at Emergency Medicine Literature of Note (emlitofnote.com) and can be found on Twitter @emlitofnote.

References

  1. American College of Emergency Physicians; American Academy of Neurology. Clinical policy: use of intravenous tPA for the management of acute ischemic stroke in the emergency department. Ann Emerg Med. 2013;61:225-43
  2. Lenzer J. Why we can’t trust clinical guidelines. BMJ. 2013;346:f3830.
  3. Australasian College for Emergency Medicine. S129 statement on intravenous thrombolysis for ischaemic stroke. Updated March 2014.
  4. Cohen D, Macdonald H. UK drug agency announces review of use of alteplase after stroke. BMJ. 2014;349:g5355.

Pages: 1 2 3 | Single Page

Topics: ACEPAmerican College of Emergency PhysiciansClinical GuidelineCritical CareEmergency DepartmentEmergency MedicineNeurologyStroketPA

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About the Author

Ryan Patrick Radecki, MD, MS

Ryan Patrick Radecki, MD, MS, is an emergency physician and informatician with Christchurch Hospital in Christchurch, New Zealand. He is the Annals of Emergency Medicine podcast co-host and Journal Club editor and can be found on Twitter @emlitofnote.

View this author's posts »

2 Responses to “ACEP Clinical Policy on Intravenous Tissue Plasmogen for Stroke Continues to Evolve”

  1. March 18, 2015

    Brian S. Alper Reply

    For a detailed analysis of the evidence on t-PA 3-4.5 hours after stroke see BMJ 2015;350:h1075 published March 17 at http://www.bmj.com/content/350/bmj.h1075

    We shared this information during the draft guideline feedback period so hopefully it will be analyzed while the policy-making is in full swing — harder to adjust after formal publication.

    We also shared with CAEP (guideline in draft state with weak recommendation against) and MHRA (the UK drug regulating agency reconsidering drug licensing)

  2. May 18, 2015

    The tPA controversy | Sinai-Grace Emergency Medicine Residency Reply

    […] of ACEP Now (it’s that monthly newsletter that we all get and occasionally read). Here is the link. Essentially, the clinical guidelines recommending tPA are changing. They used to be level A […]

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